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And there ain't nothing quite as sad
As watching your heroes die
One by one as they fall
Soon there'll be no heroes at all!
Who's going to fill their shose?

The Lt. Dan Band has grown from the occasional jam session and Chicago-area gigs to performing for charities and non-profit organizations including the United Service Organizations (USO) and Operation Iraqi Children, the latter of which was co-founded by Sinise in March 2004. In 2011, a documentary was released regarding the band and Sinise's work to benefit veterans. They frequently visit military bases in the United States and abroad, as of February 2019 they have played over 400 concerts.

Sinise was involved in building a memorial to America's three million, living, disabled veterans.  Completed in 2014, the American Veterans Disabled for Life Memorial was built due to the efforts of Sinise and the band championing the cause of the Disabled American Veterans.